Azoxystrobin

الوصف

Azoxystrobin · CAS 131860-33-8 · C22H17N3O5. UNII NYH7Y08IPM. نقطة الانصهار: 116 °C; نقطة الانصهار: MP: 114-116 °C /Technical/; الذوبانية: In water, 6 mg/L at 20 °C.

التعريف

الواصفات المحسوبة

الخصائص الفيزيائية والكيميائية

الوصف الفيزيائي وملاحظات التعامل

• White solid; [Merck Index] White crystalline solid; [MSDSonline]
• White crystalline solid
• Powdery
• Solubility (g/L, 20 °C): hexane 0.057, n-octanol 1.4, methanol 20, toluene 55, acetone 86, ethyl acetate 130, acetonitrile 340, dichloromethane 400
• Photostable.
• Chemically stable for at least 14 days at 54 °C.

تصنيف أخطار GHS

الاستخدامات الموثقة

• Used as an agricultural fungicide; [Merck Index] Used as a fungicide on golf courses and turf farms; [Reference #1]
• Azoxystrobin is produced by reaction of 4,6-dichloropyrimidine with (E)-2-hydroxymethoxyacrylate in DMF containing potassium carbonate, followed by reaction with 2-cyanophenol in DMF containing potassium carbonate.
• Bile-duct cannulated rats were given azoxystrobin radiolabelled in either the pyrimidinyl, cyanophenyl or phenylacrylate rings at 100 mg/kg bw by gavage. Comparison of the rates and routes of excretion and the profile of the metabolites showed (as previously) that there were no significant differences in the metabolism of the three differently labelled forms, thus indicating that there was minimal cleavage of the ether linkages between the aromatic rings. Experiments designed to identify metabolites were therefore
• Organic nitriles are converted into cyanide ions through the action of cytochrome P450 enzymes in the liver. Cyanide is rapidly absorbed and distributed throughout the body. Cyanide is mainly metabolized into thiocyanate by either rhodanese or 3-mercaptopyruvate sulfur transferase. Cyanide metabolites are excreted in the urine. (L96)
• Mode of action: fungicide with protectant, eradicant, translaminar & systemic properties. Powerfully inhibits spore germination &, in addition to its ability to inhibit mycelial growth, also shows antisporulant activity. Acts by inhibiting mitochondrial respiration by blocking electron transfer between cytochrome b & cytochrome c1. Controls pathogenic strains resistant to the 14 demethylase inhibitors, phenylamides, dicarboxamides or benzimidazoles.

المرادفات

Azoxystrobin; 131860-33-8; Amistar; Bankit; Heritage; Quadris; Icia-5504; DTXSID0032520; NYH7Y08IPM; CHEBI:40909; Benzeneacetic acid, 2-((6-(2-cyanophenoxy)-4-pyrimidinyl)oxy)-alpha-(methoxymethylene)-, methyl ester, (E)-; methyl (2E)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyprop-2-enoate; DTXCID8012520; methyl (2E)-2-(2-(6-(2-cyanophenoxy)pyrimidin-4-yloxy)phenyl)-3-methoxyacrylate; methyl (E)-2-[2-[6-(2-cyanophenoxy)pyrimidin-4-yloxy]phenyl]-3-methoxyacrylate; azoxy-strobin

الأسئلة الشائعة

ما رقم سجل CAS والصيغة الجزيئية لـ Azoxystrobin؟

CAS 131860-33-8; الصيغة الجزيئية C22H17N3O5; الوزن الجزيئي — g/mol.

بما هي الأسماء الأخرى التي يُعرف بها Azoxystrobin؟

Azoxystrobin, 131860-33-8, Amistar, Bankit, Heritage, Quadris.

هل يُصنّف Azoxystrobin كخطير؟

بيانات الخطر المبلغ عنها: H331, H400, H410, H370.

ما هي الخصائص الفيزيائية الرئيسية لـ Azoxystrobin؟

نقطة الانصهار: 116 °C; نقطة الانصهار: MP: 114-116 °C /Technical/; الذوبانية: In water, 6 mg/L at 20 °C; الكثافة: 1.33.

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